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Doxycycline hyclate cost increase (P=0.01). The average total cost of four regimens in this randomized study was $2,100 ($1,100 for dosed and $750 un-dosed treatment; this is greater than average in most multidrug regimens). Table 5. Factors doxycycline 100mg order Associated with the Cost of an Antibiotic for a Single-Care Dose. Two-Treatment Dose Antibiotic Dosage Antibiotics Cost Average Cost Cost Savings Cost of Two-Treatment Dose (average of the factors) Table 6. Factors Associated with the Average Total Can female take viagra Cost of a Two-Treatment Dose Antibiotics. No-Dose Combination Cost of No-Dose Combination Table 7. Factors Associated with the Average Total Cost of a No-Dose Combination Antibiotics. Dose Dosage Average Cost Savings Total Cost of the Multidrug Is sildenafil a prescription drug Regimen Total Cost of the Antibiotic Regimen No-Dose Combination $1,890 $1,500 $2,750 $1,300 $1,400 $4,200 Dose Dosage Average Cost Savings No Dose Combination Dosage $2,100 $1,500 $3,750 Dose $1,900 $1,400 Dosage Average Cost Savings No Dose Combination Dosage $2,100 (no-dose group) — Total Cost of Antibiotic Regimen $3,250* $3,000 $3,250 $4,950 Total Cost of Antibiotic Regimen No-Dose Combination $4,900 $4,100 $5,000 *$20 (two-drug therapy dose) is an average of total cost a four-drug regimen and one-drug (and represents a 50% cost savings over the two-drug regimen). Cost is a function both of the time it consumes to administer the drugs and of benefits derived from them. Although the relative time savings of one drug over another often is cited, it also important to know the relative cost savings attributable to each. The question of whether a drug really is better in preventing pneumonia or reducing bacterial overgrowth versus simply being cheaper is a key issue in clinical trials. When the data are summarized in Table 8, it also becomes clear that cost savings are dependent on several other factors, including whether a drug is efficacious. For example, as shown in Table 9, there is a positive correlation between cost savings and effectiveness. Other factors that are associated with cost savings do not necessarily correlate with the degree of effectiveness. TABLE 8. Cost and Benefits of Antimicrobial Combinations for a Single-Care Dose. Cost and Benefit No-Dose Combination $857 Average Cost Savings Total of Antibiotic Regimen No-Dose Combination $2,100 Dose $1,800 $1,200 $750 Average Cost Savings Total of Antibiotic Regimen No-Dose Combination $1,300 (no-dose group) Total Savings No-Dose Combination $1,300 Maximum Benefit $1,000 — Cost Reduction No cost (no-dose group) Table 9. Correlation Between Average Total Cost of a No-Dose Combo Antibiotics and Effectiveness. Table 10. Effectiveness of Antimicrobial Combinations. Antibiotic Combination Cost Benefits Effectiveness Savings in Days of Pneumonia No-Dose Combination $1,100* 15* 0 4 0 $0 Dose A B No-Dose Combination $1,200* 15* 0 5 Dose B A No-Dose Combination $1,300* 15* 0 Dose A B *These benefits are based on data from randomized controlled trials. Antibiotic Combination Cost Benefits Effectiveness Savings in Days of Pneumonia No-Dose Combination.

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